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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb98d120b688406f3b680fb2a595fa325e8a6495ecc0a19f8932258788b9994a' 
  AND token = 'S2AehlrQsLD1h9aA41Hh7zSi5REC8aedkteMEHe77Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}