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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '451c7315a6ac6cf2ad2f90438518b8ce62f300f1493d14c77be0e2aca4a4a0ea' 
  AND token = 'znY0jMyDMRvGN/Wqtv9pD5FnwuaBigLE8xzl2HN3SVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}