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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '686a25f5078292def9a112694020699ba04d526d0c52efc1389cda6cfdc3b612' 
  AND token = 'SbWSr0Vj5xY3D5+sp/nzhS+shuxk1FNg6zDFnPBo3pw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}