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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '361a3d46686201f36ff7a1f7897aa351a08e8662df55401cbb5017d912192548' 
  AND token = 'WaWs+MZkzUe5GhHPrbpfZulZk+mqK4ed6+EzRvimbec=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}