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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fb1c83d2293962bf9e9c358695310e1e395d4acdb0bfe279b419af45015e32f' 
  AND token = 't9hTInCVyeOZ418Mt8l2t5qZhH3KKtBrPBSs3VcIJ7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}