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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0491126685c4eae17030c4d1e8dafda69597c1c68b7cd0222fe810c03fda539f' 
  AND token = 'PAaBjU44qfgyZYtshJLggGuOsIN2JTW7yY3zsW9MTpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}