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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '079b7017ef5a1536c7214722973d635d2e7899c685f7b8a70b4a47d81b97befd' 
  AND token = 'in52QrP2Qwd9PJZpRm5NG2/5NeT4Km3oyrtfmykz4fY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}