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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e6067875eb62902f6efdc6f50c95fc3bddcf086e24f024d620ded683a4789f1' 
  AND token = 'RtHDyLp3HGnGDatU/4AqUihMXQxI3fJ7q6bqk0yfPog=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}