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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05e5a85eaf3c05372644f87e2333c9abca76e7f6efc627e6d09b8492fb945f78' 
  AND token = '9igUtVHUUbA61oY2D49dbrQxW5iYdTwX07aZSLvI6uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}