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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e469121e1e91a53bb54f8e5ccdf187eb57f358022aa91709899e91d7d1a4bb0' 
  AND token = '5wZgo3jiuF8Nx8BLuVciVRjZx96kCq9JdQK6qnllAao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}