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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '801275c4314babbde04b31d9eefb14af4bc27a78f5e138b56e17090221dc2b4a' 
  AND token = 'p1aI7Qa2JFqlXX6cq8iEv5SJEy8XN/DSSLtSFzRG8W4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}