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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8341c175eb2daa7d435670f5ef3abb9e110fec8cd4c9aa3622e97c15d4a5f3f4' 
  AND token = 'paPGk88hHIF0lwUNYAyuby1EW3JNPDq/OZ0MPCMCRhw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}