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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f3326e8114c542eb5326ea7c50a9fa444c3d209edc4555c097507b74c34ef7' 
  AND token = 'iDCbkjlCWd+popIYo/+Odf7vBs3+aPlZ1osKuMnEBSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}