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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '58ce1a02d8387e23a4a8840c9430352c1ec8a720d9cce490433b4c3f164289bd' 
  AND token = 'UwjrWCrij6E7eStmQ2+zxvnUCMjLtg8404KCWFFK8Do=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}