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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1edbcc0d1b5018f989f73f11d0dede407273e85f3882ec2391444b26dee9172' 
  AND token = 'Ei5ot8DBi+ai+X7twAfOL9dDQAsA3rZ2xUiN4ok5uS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}