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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eced365c9822e8dcb37f2cd86f65c75dec1e6f1311df484921f5caccfdc2556' 
  AND token = '+u+qKq17ka8wFCx6q0sH/PDndW1uS945p7ooGqcZCro=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}