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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af37ef6ba97a9eefe2d14b6505fc48154e004cb21772192c3d7d655fec977134' 
  AND token = 'vkpzP1ajMT+tYIhT5dGRnb8Ybg+GLaOZGF7WawZiiks=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}