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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7135c0ee0cf59a3c51a7c3d99d868cf61b81ee07fca78c1ebed12d100864403f' 
  AND token = 'go1Y8upw1vb/KrNMD+5nYNy3KREJW1DrOG6ljcD7mZg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}