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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3b165137a0d30a4939d4873de5b0da9c21a3ffa1a5d17b41bc4dd94d5907986' 
  AND token = 'tBTto+YICS9w9w4unwwUovWG8FkRVPKsYIcCedbwXoI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}