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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c279e732e7f1d75c75032f78edb0bb4cd4f70e461fcd5a30c5d063a731e1934d' 
  AND token = 'fo6WNXry8ma0zwyUcftYME5wzT+d6fOMfzsUths1CsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}