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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777d08bcdfd6efb6bfe14de674c632821f471dc920037b3b50c4e29b7d718645' 
  AND token = 'OhMy2KMvhMHIYGy+dzFd3eM06G/o5uhyv5kn/DsZ6hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}