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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ed8505a06f0bbe9348a707c3400ad0dafc84ad8aaa3504559b3508c3e122fcd' 
  AND token = 'yzQEyBkL51Ue2W718BhDsviGVe8S5Dkxz1wyLfgDOps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}