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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c45255e4d48a9917b86e4bbd66c6df8afe3eeff04f8c670f9db42eb8d9e38a7' 
  AND token = '4l/RsTZeuaAotNoKUmrS5+s97Y/UUinKq8uwDPk0QzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}