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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8228e603cf7d143de98c313e0bed387d98beac8b36e9796a0a1da1b1ad6dd368' 
  AND token = 'XMem6yB05sh10EsFyUyK7buJI/jR2hxruiGBLVIDelY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}