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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a5cfabafe789c11904441f57df1afa2132b6d5eeb00e1cdbcbf6054d75188bd' 
  AND token = 'e50Y66sS1kaBIXGoBXGF8BTv1Ua7OLGU/1HDO2ZQpyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}