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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2159481ab6105549d7dee909630eee2eee2f7cfb5e23bd7814e406055f3b41ad' 
  AND token = 'l2/bb/MC2TC3ehJ224LwRA3la7eoqrekPPozpP8+Lbw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}