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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bc90de96fb006e46d0f0ffa6a9638712cd5f243725280b7e90e5f3fdb74d571' 
  AND token = 'xV2w43IiaU5/47fmukXnS60bSglzK701dKAXHd/LKPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}