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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb54a7e9d5b635584c11c496584000eb90dad2e105c5a5f3b56395535b62af6f' 
  AND token = 'S45npg9QoBTaF+o6GHA1uMDChZTK7z6qGovUKLbBe68=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}