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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f8266ddc6ff0b737b492d088c0e915f1f580f0271cc572da8fd7f3b60b8e78b' 
  AND token = 'pIasNoG1LSq5aiqqEt9Vbp/spv2X+Kn4Ob3EIC7RlhM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}