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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '477a2ae3566d2d8bfc68e89c582a01dd2231da5a1a859ee42fdaab7a7b0c3a53' 
  AND token = 'Yf6R8ONgyJuWTKLo513oGVNt/VV/2WVl4uwxCse4Z7E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}