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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f0747ba79fd824fcd5e5abd4f80dc1cffaa9963ddfa1d1bb414ca2dc10b399b' 
  AND token = '4Q8wyMDPWzdRLe7iVLE4EGACgi3WhC/Fn+QzZqB0pmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}