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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c6191d40162675f7bff1c41b1bcfc6215bbb61bcc14d0e7345e4dd393de5f99' 
  AND token = 'KoEnw49Wyvn3050qABHR+vCg1heC69JrYhM1LjHvTF0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}