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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8169e1706a843cafbf7ee9ec4078ae4288b86df5097d2968a5d6a3ed08bf3e29' 
  AND token = 'vq60abdt7D4NlBGcATt1mw+UY4oM7LonQM4/tgXCJB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}