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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1f0500097efffa3d33113c8d728684358ff775487b849c0df1eef7e9c8c2424' 
  AND token = 'dN6O2hNWm9zsiWy+cTWJCdXq/sV00k+m0Yoz1IB5/lI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}