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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '901d501257fce7ae355440c949a425eade096cf833013f5adfb080bd8b3b9d28' 
  AND token = 'rx5mg//eTjLQFR1jPbcs/MHO+w4y2udYGGFRyBdwJJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}