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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '481c1350b17ddce177e23bf7219a140bd29cc22fc3e48d85213a1bfe8d7f36f3' 
  AND token = 'hkx2yYD+n7IJsrrTuVG15u/jhXedml3IHdpSp3lZlMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}