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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9ef484c7b00d99e544465052235e305e096dbbc6471610a9e237e9270e24d92' 
  AND token = 'w6UMryhaR9930HBhb+G+8llMAx8mdW/AkPN9WSkF1Us=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}