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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6221883e3c7839ad56064e99920fc94674d8d0a1c55ae15ee710f68eb6ad764' 
  AND token = 'pu648p87FDBAT7jPFqkl6CgmUeVmQLeKTp+74rFW8P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}