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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd48765ee850c8fde158fb5f119ce1de390619ea49a3aa6c193d1f24956f5d059' 
  AND token = 'KfyQ323qLBefS9xvOb4YBl+RBj7VhGxl1cKVAZ2d8UQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}