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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18c227efc0172fb99194beb00b9f33671c6834a56b6d251937e189188255e03e' 
  AND token = 'yvCtrjUW6ZB0TfBy1PWDProw/cDPC2RpKcbosiVppMQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}