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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '553c1333c2e3e53a3a06e222db8b6a7cc438766983b0088568ccf261e1b7e693' 
  AND token = 'grA3Fi3fjT64QyNBnV+TNYRtiAxxqAXpHdp3qspsNWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}