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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5d932bfb5151b213b2103c1cc12c87bc6d61cf65a6cce2be46b49c54afce725' 
  AND token = 'GcMKI5Un8AMT0YYJSwCbqihP/DuNUXan3bU441SGzUE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}