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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aac4df4dbac3ea8675d64caf1babba2649649f1928a84a9dea669381e31e892' 
  AND token = 'khF4r2cGHx4zW8C60LStEU50gRjfsmvCElTyzqa24MM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}