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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b6c20ebfa0ab0e5dd82a92e03e2082424d4ffa72ddae255cf409b9c6fb05884' 
  AND token = 'Zsg1GROKfPsXalXGkRRa1UQp2YhlFZ3AkytabR+ZxgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}