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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251c745b1801b9b69651b1cc58d6156584445e739292e87a10d0d365babf2d07' 
  AND token = 'JA0BmN9xk+wJlqyG60EmlcoiQ+T4A1fH7bjtluNiHlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}