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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4600e6c6ab1c2f0ee7d8d2d49274ff9505296dad74854056503fc994552aef0' 
  AND token = 'AOfhVx0DgpF2DvxQR2KFLQJ83eSra/wRx3jxVjRXlBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}