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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9a6d4e8ecc09a7b7ec9786a2e101031d338a3440c72bfb1940526260ce4f3f1' 
  AND token = 'ASEA8dI++OAcgedfX01K2XgHAtw4orV+DhYcBLEBixM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}