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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1bfcdcc73c8065ed096814f19882a3193ecb202a94b8d8c765d5bc0777caf0ce' 
  AND token = 'h+YXhO3gz2OrGRKR7c9b/nDg5+I3rVyakjgLA0UBH1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}