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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33598d140d430377f661d1ad781669e144724fd9202cfe7811c12849f4d5f81a' 
  AND token = 'q9YIzoEh1ap1u0HzQfdKai6pRVTrNwoaQHdf0+i5KgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}