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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ae09699a8465b0dcd565f9fb4b463d60616245b72cdf0e7772d98bdc3832b41' 
  AND token = 'IhYHtjZp0WP0dCz+Drxk7+xf+rQAMMWhhuzd+t2YZ6Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}